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2022

Continuous-flow stereoselective reduction of prochiral ketones in a whole cell bioreactor with natural deep eutectic solvents

Annunziata, F.| Guaglio, A.| Conti, P.| Tamborini, L.| Gandolfi, R.

Green Chem., 24, 950 (2022)

DOI: 10.1039/d1gc03786b

Efficient 2-Step Enzymatic Cascade for the Bioconversion of Oleuropein into Hydroxytyrosol

Catinella, G.| Donzella, S.| Borgonovo, G.| Dallavalle, S.| Contente, M.L.| Pinto, A

Antioxidants, 11(2), 260 (2022)

DOI: 10.3390/antiox11020260

Recent advances in the synthesis of naturally occurring tetronic acids

Princiotto, S.| Jayasinghe, L.| Dallavalle, S.

Bioorganic Chemistr,y 119, 105552 (2022)

DOI: 10.1016/j.bioorg.2021.105552

Whole cells of recombinant CYP153A6-E. coli as biocatalyst for regioselective hydroxylation of monoterpenes

Cannazza, P.| Rabuffetti, M.| Donzella, S.| De Vitis, V.| Contente, M.L.| de Oliveira, M.C.F.| de Mattos, M.C.| Barbosa, F.G.| de Souza Oliveira, R.P.| Pinto, A.| Molinari, F.| Romano, D.

AMB Express, 12:48 (2022)

DOI: 10.1186/s13568-022-01389-8

From saffron residues to natural safranal: Valorization of waste through a β-glucosidase

Catinella, G.| Borgonovo, G.| Dallavalle, S.| Contente, M.L.| Pinto, A.

Food and Bioproducts Processing, 131, 144–148 (2022)

DOI: 10.1016/j.fbp.2021.11.002

From Batch to Continuous Flow Bioprocessing: Use of an Immobilized γ-Glutamyl Transferase from B. subtilis for the Synthesis of Biologically Active Peptide Derivatives

Robescu, M.S.| Annunziata, F.| Somma, V.| Calvio, C.| Morelli, C.F.| Speranza, G.| Tamborini, L.| Ubiali, D.| Pinto, A.| Bavaro, T.

J. Agric. Food Chem., 70, 13692−13699 (2022)

DOI: 10.1021/acs.jafc.2c03702

Exploring the Interaction of G-quadruplex Binders with a (3 + 1) Hybrid G-quadruplex Forming Sequence within the PARP1 Gene Promoter Region

Mazzini, S.| Princiotto, S.| Artali, R.| Musso, L.| Aviñó, A.| Eritja, R.| Gargallo, R.| Dallavalle, S.

Molecules , 27(15), 4792 (2022)

DOI:10.3390/molecules27154792

3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death

Pacchiana, R.| Mullappilly, N.| Pinto, A.| Bova, S.| Forciniti, S.| Cullia, G.| Pozza, E.D.| Bottani, E.| Decimo, I.| Dando, I.| Bruno, S.| Conti, P.| Donadelli, M.

Cancers, 14(13), 3153 (2022)

DOI: 10.3390/cancers14133153

Biocatalyzed Synthesis of Vanillamides and Evaluation of Their Antimicrobial Activity

Pinna, C.| Martino, P.A.| Meroni, G.| Sora, V.M.| Tamborini, L.| Dallavalle, S.| Contente, M.L.| Pinto, A.

J. Agric. Food Chem., 70, 223−228 (2022)

DOI: 10.1021/acs.jafc.1c06213

Enzymatic continuous-flow preparation of nature-inspired phenolic esters as antiradical and antimicrobial agents

Annunziata, F.| Contente, M.L.| Anzi, V.| Donzella, S.| Conti, P.| Molinari, F.| Martino, P.A.| Meroni, G.| Sora, V.M.| Tamborini, L.| Pinto, A.

Food Chemistry, 390, 133195 (2022)

DOI: 10.1016/j.foodchem.2022.133195

Enzymatic amide bond formation: synthesis of aminooxo-acids through a Mycobacterium smegmatis acyltransferase

Christodoulou, M.S.| Contente, M.L.| Dallavalle, S.| Pinto, A.

Green Chem., 24, 4432-4436 (2022)

DOI: 10.1039/D2GC00655C

Mycobacterium smegmatis acyltransferase: The big new player in biocatalysis

Cannazza, P.| Donzella, S.| Pellis, A.| Contente, M.L.

Biotechnology Advances, 59, 107985 (2022)

DOI: 0.1016/j.biotechadv.2022.107985

Mimicking Natural Metabolisms: Cell-Free Flow Preparation of Dopamine

Donzella, S.| Colacicco, A.| Nespoli, L.| Contente, M.L.

ChemBioChem, 23, e202200462 (2022)

DOI: doi.org/10.1002/cbic.202200462

Investigation of the Interaction between Aloe vera Anthraquinone Metabolites and c-Myc and C-Kit G-Quadruplex DNA Structures

Dallavalle, S.| Artali, R.| Princiotto, S.| Musso, L.| Borgonovo, G.| Mazzini, S.

Int. J. Mol. Sci., 23(24), 16018 (2022)

DOI: 10.3390/ijms232416018

Screening methods for enzyme-mediated alcohol oxidation

Contente, M.L.| Marzuoli, I.| Iding, H.| Wetzl, D.| Puentener, K.| Hanlon, S.P.| Paradisi, F.

Scientific Reports,  12, 3019 (2022)

DOI: 10.1038/s41598-022-07008-7

Correlation between Perturbation of Redox Homeostasis and Antibiofilm Capacity of Phytochemicals at Non-Lethal Concentrations

Christodoulou, M.S.| Villa, F.| Pinto, A.| Cappitelli, F.

Antioxidants, 11(12), 2451 (2022)

DOI: 10.3390/antiox11122451

Ruthenium-Catalyzed Decarboxylative Rearrangement of 4-Alkenyl-isoxazol-5-ones to Pyrrole Derivatives

Molteni, L.| Loro, C.| Christodoulou, M.S.| Papis, M.| Foschi, F.| Beccalli, E.M.| Broggini, G.

Eur. J. Org. Chem., e20220049 (2022)

DOI: 10.1002/ejoc.202200496

Antitumor activity of novel POLA1-HDAC11 dual inhibitors

Dallavalle, S.| Musso, L.| Cincinelli, R.| Darwiche, N.| Gervasoni, S.| Vistoli, G.| Guglielmi, M.B.| La Porta, I.| Pizzulo, M.| Modica, E.| Prosperi, F.| Signorino, G.| Colelli, F.| Cardile, F.| Fucci, A.| D’Andrea, E.L.| Riccio, A.| Pisano, C.

 Eur. J. Med. Chem., 228, 113971 (2022)

DOI: 10.1016/j.ejmech.2021.113971

Synthesis and biological activity evaluation of 3-(hetero) arylideneindolin-2-ones as potential c-Src inhibitors

Princiotto, S.| Musso, L.| Manetti, F.| Marcellini, V.| Maga, G.| Crespan, E.| Perini, C.| Zaffaroni, N.| Beretta, G.L.| Dallavalle, S.

J. Enzyme Inhib. Med. Chem., 37(1), 2382–2394 (2022)

DOI: 10.1080/14756366.2022.2117317

Flow Synthesis of Nature-Inspired Mitochondria-Targeted Phenolic Derivatives as Potential Neuroprotective Agents

Pecora, D.| Annunziata, F.| Pegurri, S.| Picone, P.| Pinto, A.| Nuzzo, D.| Tamborini, L.

Antioxidants, 11(11), 2160 (2022)

DOI: 10.3390/antiox11112160

Synthesis and Investigation of the G-Quadruplex Binding Properties of Kynurenic Acid Derivatives with a Dihydroimidazoquinoline-3,5-dione Core

Mazzini, S.| Princiotto, S.| Musso, L.| Passarella, D.| Beretta, G.L.| Perego, P.| Dallavalle, S.

Molecules  27(9), 2791 (2022)

DOI: 10.3390/molecules27092791

Fatty Acids/Tetraphenylethylene Conjugates: Hybrid AIEgens for the Preparation of Peptide-Based Supramolecular Gels

Impresari, E.| Bossi, A.| Lumina, E.M.| Ortenzi, M.A.| Kothuis, J.M.| Cappelletti, G.| Maggioni, D.| Christodoulou, M.S.| Bucci, R.| Pellegrino, S.

Front. Chem. 10, 927563 (2022)

DOI: 10.3389/fchem.2022.927563