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2021

Biocatalytic Approaches for an Efficient and Sustainable Preparation of Polyphenols and Their Derivatives

Contente, M.L.| Annunziata, F.| Cannazza, P.| Donzella, S.| Pinna, C.| Romano, D.| Tamborini, L.| Barbosa, F.G.| Molinari, F.| Pinto, A.

J. Agric. Food Chem. 69, 46, 13669–13681, (2021)

DOI: 10.1021/acs.jafc.1c05088

Investigation of the complexes formed between parp1 inhibitors and parp1 g-quadruplex at the gene promoter region

Dallavalle, S.| Princiotto, S.| Mattio, L.M.| Artali, R.| Musso, L.| Aviñó, A.| Eritja, R.| Pisano, C.| Gargallo, R.| Mazzini, S.

Int. J. Mol. Sci. 2021, 22(16), 8737

DOI: doi.org/10.3390/ijms22168737

Multi-gram preparation of cinnamoyl tryptamines as skin whitening agents through a chemo-enzymatic flow process

Padrosa, D.R.| Contente, M.L.

Tetrahedron Letters 86 153453 (2021)

DOI: 10.1016/j.tetlet.2021.153453

Xanthohumol Pyrazole Derivative Improves Diet-Induced Obesity and Induces Energy Expenditure in High-Fat Diet-Fed Mice

Paraiso, I.L.| Mattio, L.M.| Alcázar Magaña, A.| Choi, J.| Plagmann, L.S.| Redick, M.A.| Miranda, C.L.| Maier, C.S.| Dallavalle, S.| Kioussi, C.| Blakemore, P.R.| Stevens, J.F.

ACS Pharmacol. Transl. Sci. 4 (6) 1782–1793, (2021)

DOI: 10.1021/acsptsci.1c00161

Agarose vs. Methacrylate as material supports for enzyme immobilization and continuous processing

Benítez-Mateos, A.I.| Contente, M.L.

Catalysts 2021, 11(7), 814

DOI:10.3390/catal11070814

Structural insights into the desymmetrization of bulky 1,2-dicarbonyls through enzymatic monoreduction

Rabuffetti, M.| Cannazza, P.| Contente, M.L.| Pinto, A.| Romano, D.| Hoyos, P.| Alcantara, A.R.| Eberini, I.| Laurenzi, T.| Gourlay, L.| Di Pisa, F.| Molinari, F.

Bioorg. Chem. 108, 104644, (2021)

DOI: 10.1016/j.bioorg.2021.104644

Structural investigation and molecular modeling studies of strobilurin‐based fungicides active against the rice blast pathogen pyricularia oryzae

Kunova, A.| Palazzolo, L.| Forlani, F.| Catinella, G.| Musso, L.| Cortesi, P.| Eberini, I.| Pinto, A.| Dallavalle, S.

Int. J. Mol. Sci. 22(7), 3731, (2021)

DOI: 10.3390/ijms22073731

New antimicrobials based on the adarotene scaffold with activity against multi-drug resistant staphylococcus aureus and vancomycin-resistant enterococcus

Princiotto, S.| Mazzini, S.| Musso, L.| Arena, F.| Dallavalle, S.| Pisano, C.

Antibiotics  10(2), 126, (2021)

DOI: 10.3390/antibiotics10020126

Flow biocatalysis 101: Design, development and applications

Benítez-Mateos, A.I.| Contente, M.L.| Roura Padrosa, D.| Paradisi, F.

React. Chem. Eng., 6, 599-611, (2021)

DOI:/10.1039/D0RE00483A

Apoptosis-mediated anticancer activity in prostate cancer cells of a chestnut honey (Castanea sativa L.) quinoline–pyrrolidine gamma-lactam alkaloid

Beretta, G.| Moretti, R.M.| Nasti, R.| Cincinelli, R.| Dallavalle, S.| Montagnani Marelli, M.

Amino Acids 53, 869–880 (2021)

DOI: doi.org/10.1007/s00726-021-02987-9

Cladosporols A and B, two natural peroxisome proliferator-activated receptor gamma (PPARγ) agonists, inhibit adipogenesis in 3T3-L1 preadipocytes and cause a conditioned-culture-medium-dependent arrest of HT-29 cell proliferation

Rapuano, R.| Ziccardi, P.| Cioffi, V.| Dallavalle, S.| Moricca, S.| Lupo, A.

BBA – General Subjects 1865, 129973, (2021)

DOI: 10.1016/j.bbagen.2021.129973

Ultrasound-assisted solvent-free synthesis of 3, 4-dihydropyrimidin-2(1H)-ones/thiones using polyindole as a recyclable catalyst

Handore, K.N.| Chabukswar, V.V.| Pawar, D.| Dallavalle, S.

Polym-Plast Tech Mat 60(3), 306-315, (2021)

DOI: 10.1080/25740881.2020.1811313

Promising Non-cytotoxic Monosubstituted Chalcones to Target Monoamine Oxidase-B

Iacovino, L.G.| Pinzi, L.| Facchetti, G.| Bortolini, B.| Christodoulou, M.S.| Binda, C.| Rastelli, G.| Rimoldi, I.| Passarella, D.| Di Paolo, M.L.| Dalla Via, L.

ACS Med. Chem. Lett.  12(/), 1151–1158, (2021)

DOI: doi.org/10.1021/acsmedchemlett.1c00238

Biocatalyzed flow oxidation of tyrosol to hydroxytyrosol and efficient production of their acetate esters

Annunziata, F.| Contente, M.L.| Pinna, C.| Tamborini, L.| Pinto, A.

Antioxidants, 10(7), 1142, (2021)

DOI: 10.3390/antiox10071142

G-quadruplex binding properties of a potent PARP-1 inhibitor derived from 7-azaindole-1-carboxamide

Dallavalle, S.| Musso, L.| Artali, R.| Aviñó, A.| Scaglioni, L.| Eritja, R.| Gargallo, R.| Mazzini, S.

Sci Rep 11, 3869 (2021)

DOI: 10.1038/s41598-021-83474-9

Antioxidant activity of citrus limonoids and investigation of their virucidal potential against SARS-CoV-2 in cellular models

Magurano, F.| Sucameli, M.| Picone, P.| Micucci, M.| Baggieri, M.| Marchi, A.| Bucci, P.| Gioacchini, S.| Catinella, G.| Borgonovo, G.| Dallavalle, S.| Nuzzo, D.| Pinto, A.

Antioxidants 10(11), 1794 (2021)

DOI:  10.3390/antiox10111794

Plant-Derived Stilbenoids as DNA-Binding Agents: From Monomers to Dimers

Platella, C.| Mazzini, S.| Napolitano, E.| Mattio, L.M.| Beretta, G.L.| Zaffaroni, N.| Pinto, A.| Montesarchio, D.| Dallavalle, S.

Chem. Eur. J., 27, 8832 – 8845 (2021)

DOI:10.1002/chem.202101229

Grapevine stilbenoids as natural food preservatives: Calorimetric and spectroscopic insights into the interaction with model cell membranes

Saitta, F.| Mazzini, S.| Mattio, L.| Signorelli, M.| Dallavalle, S.| Pinto, A.| Fessas, D.


Food Funct.12, 12490-12502 (2021)

DOI: 10.1039/d1fo01982a

Exploring the interaction of curaxin cbl0137 with g-quadruplex dna oligomers

Dallavalle, S.| Mattio, L.M.| Artali, R.| Musso, L.| Aviñó, A.| Fàbrega, C.| Eritja, R.| Gargallo, R.| Mazzini, S.

Int. J. Mol. Sci. 22(12), 6476 (2021)

DOI: 10.3390/ijms22126476

Design and Synthesis of Hsp90 Inhibitors with B-Raf and PDHK1 Multi-Target Activity

Pinzi, L.| Foschi, F.| Christodoulou, M.S.| Passarella, D.| Rastelli, G.

ChemistryOpen 10, 1177 – 1185 (2021)