We are pleased to announce that our recent article, “Streamlining Vorinostat Synthesis: A Chemoenzymatic Continuous Flow Approach”, has been highlighted on the cover of the European Journal of Organic Chemistry.
In this study, we developed a chemo-enzymatic strategy for the synthesis of the anticancer drug vorinostat, combining chemical acylation with a lipase-catalyzed condensation. The process, successfully translated from batch to continuous flow, achieves high efficiency in reduced reaction time and with lower environmental impact.
This recognition underscores our ongoing commitment to advancing sustainable synthetic methodologies for pharmaceutically relevant molecules.
